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In 1979 allegra drums reviews Japanese built vessel was launched as the Puma for Pamp;O but was chartered to BI Line and renamed Tipperary. During the 1980's the vessel first operated a allegr new Dublin-Fleetwood route jointly operated with Pamp;O, alongside Tipperary's Ro-Ro sister, Ibex. The Pamp;O brand name Pandoro cleverly stood for P and O Ro, their roll-on roll-off freight division. Cut-away deck profile of M. Tipperary and sistership of M. Ibex.

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Given their role in antigen presentation, HSPs are useful as immunologic adjuvants in boosting the response to a vaccine. Furthermore, some researchers speculate that HSPs may be involved in binding protein fragments from dead malignant cells and presenting them to the immune system. Therefore HSPs may be useful for increasing the effectiveness of cancer vaccines. Intracellular heat shock proteins are highly expressed in cancerous cells and are essential to the survival of these cell types. Hence small molecule inhibitors of HSPs, especially Hsp90 show promise as anticancer agents. The potent Hsp90 inhibitor 17-AAG is currently in clinical trials for the treatment of several types of cancer.

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