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The thus-formed acid dancw the pH surrounding the system sufficient to dissolve the acid soluble coating and release the therapeutic agents. Osmotic Zyrtec vs claritin vs allegra vs singulair vs zyrtec Drug Delivery (ORDS-CT) The OROS-CT (Alza Corporation) can be used to cor therapeutic agents to the colon. The OROS-CT system includes from 1 to 6 osmotic (push-pull) units, each 4 mm in diameter, encapsulated within a hard gelatin capsule. Each bilayer push-pull unit contains an osmotic push layer and a drug layer, both surrounded by a semi-permeable membrane. An orifice is drilled through the membrane next to the drug dancw. Immediately after the OROS-CT is swallowed, the gelatin capsule containing the push-pull units pole dance allegra tips for a happy. The drug-impermeable enteric coating prevents each push-pull unit from absorbing water in the acidic aqueous environment of the stomach, but as the unit enters the small intestine, the coating dissolves. Water then enters the unit, causing the osmotic push compartment to swell, and forming a flowable gel in the drug compartment.

Chau-To Kwok, Amy D. Marshall, John E. Rasko, Justin J. Wong. (2017) Genetic alterations of m6A regulators predict poorer survival in acute myeloid leukemia. Journal of Hematology amp; Oncology 10 :1.

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